Diabetes ketoacidosis in L-asparaginase therapy
نویسندگان
چکیده
منابع مشابه
Diabetes ketoacidosis in L-asparaginase therapy
Case E.C, 10 years old female brought to the ER due abdominal pain. Patient is a diagnosed case of B-Cell Acute Lymphoblastic Leukemia (ALL) thru clinical symptoms, laboratory work-ups and flow cytometry since 2 months prior to her present admission. She has been receiving 8 doses of L-asparaginase (leunase) and Prednisone (60mg/day for a week then 40mg/day for 3 weeks) for almost one month bef...
متن کاملAcute Pancreatitis and Diabetic Ketoacidosis following L-Asparaginase/Prednisone Therapy in Acute Lymphoblastic Leukemia
Acute pancreatitis and diabetic ketoacidosis are unusual adverse events following chemotherapy based on L-asparaginase and prednisone as support treatment for acute lymphoblastic leukemia. We present the case of a 16-year-old Hispanic male patient, in remission induction therapy for acute lymphoblastic leukemia on treatment with mitoxantrone, vincristine, prednisone, and L-asparaginase. He was ...
متن کاملTransient diabetes mellitus secondary to L-asparaginase
Secondary Diabetes Mellitus (DM) has been associated in about 1-14% of patients with hematologic malignancy treated with L-asparaginase. An 11-year old Filipino female, diagnosed with Acute Lymphoblastic Leukemia, developed hyperglycemia associated with polyuria and polydipsia while on-going induction chemotherapy. There was no family history of diabetes mellitus. Chemotherapy drugs included L-...
متن کاملTransient hyperthyroidism following L-asparaginase therapy for acute lymphoblastic leukemia.
The effect of L-asparaginase on the thyroid gland has not been well documented. We report the first two cases of hyperthyroidism associated with thyroid nodule following L-asparaginase therapy for acute lymphoblastic leukemia (ALL). The thyroid function abnormalities were not severe, short-lived and did not require specific therapy.
متن کاملHyponatraemia in diabetes without ketoacidosis.
At diagnosis six of 18 diabetic children had hyponatraemia with hyperglycaemia but no signs of dehydration or lipaemia. With insulin treatment alone plasma sodium concentrations in two children returned to normal. These children do not require specific treatment to correct the hyponatraemia.
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ژورنال
عنوان ژورنال: International Journal of Pediatric Endocrinology
سال: 2013
ISSN: 1687-9856
DOI: 10.1186/1687-9856-2013-s1-p21